The Entourage Effect

By now, we’ve explored the two most well-known cannabinoids—THC and CBD—but cannabis is far more complex than just these two. In reality, the plant contains over a hundred cannabinoids, along with aromatic compounds known as terpenes. Together, these compounds interact in what’s called the entourage effect, a phenomenon where different elements of cannabis work synergistically to create unique effects beyond what any single compound can achieve alone.
Why the Entourage Effect Matters
Unfortunately, in the world of commercial cannabis, many consumers fixate on THC percentage as the sole indicator of potency and quality. But this oversimplification misses the bigger picture. The true impact of cannabis comes from a blend of cannabinoids and terpenes, each playing a crucial role in shaping the overall experience.
The Role of Minor Cannabinoids
Beyond THC and CBD, the plant is packed with minor cannabinoids like CBG, CBN, and CBC, each with its own distinct properties. CBG can promote focus and alertness, while CBN is known for its sedative effects. When combined, these compounds influence how the cannabis affects the user, making a high-THC product without supporting cannabinoids a far different experience than a well-balanced one.
The Power of Terpenes
Terpenes—the compounds responsible for the scent and flavor of cannabis—are another key part of the entourage effect. These natural oils not only dictate aroma but also influence the type of high you experience. For instance, myrcene, a terpene found in mangoes, can contribute to a sedative, couch-lock effect, while limonene, commonly found in citrus fruits, is known for its uplifting and energetic properties.
Rethinking Sativa and Indica
The traditional classifications of sativa and indica are often misleading. Many assume that sativas are always energizing and indicas are always sedating, but the reality is more nuanced. An older, degraded sativa can make you sleepy, while a freshly harvested indica with the right terpene profile may be uplifting. Rather than relying solely on strain names, understanding the full cannabinoid and terpene content is key to predicting effects.
Looking Beyond THC Percentages
High THC levels don’t necessarily equate to a better experience. A strain with 30% THC but little terpene or cannabinoid complexity may feel flat, while a 20% THC strain with a rich mix of minor cannabinoids and terpenes can provide a more well-rounded and enjoyable high. Consumers who chase THC numbers alone may miss out on the depth and nuance of cannabis.
The Takeaway: Cannabis is Complex
The entourage effect is what makes cannabis truly special. It’s not just about THC or CBD—it’s about how all the plant’s compounds work together to create effects that are greater than the sum of their parts. As the industry evolves, education is crucial. By understanding the full spectrum of cannabinoids and terpenes, consumers can move beyond chasing THC percentages and instead seek out the most effective, enjoyable, and beneficial cannabis experiences.